What is steroid aromatization

When taking steroids, there are number of process that happens in the body. Along with anabolic effect, steroids may cause some serious side effects that every bodybuilder fears of. Most of them are estrogenic issues caused by the strong aromatization.

Bodybuilders search on the internet for low aromatizing steroids or even for those who do not aromatize at all. This is a wrong approach, since all steroids aromatize, but in different degree.

To better understand why all steroids carry the risk of aromatization and how bad it is for your health, you will have to know, first of all, what aromatization means, what cause it and how can be prevented its downsides. Yes, downsides, since generally it is good process for body and you will see in this article why.

Aromatization is not triggered by steroid use. It is a natural process during which testosterone is transformed into estrogen. This process is carried out by a special enzyme in our body called aromatase, thus the whole processed was called aromatization. The main task or aromatization is the synthesis of cholesterol and fats. But it changes when body feels a testosterone boost.

Human body has a very interesting characteristic: it tend to ensure a balance in all it has-muscles, hormones, temperature and others. This stage is known as homeostasis. When big amounts of testosterone enters the body, homeostasis try to put the things in order by triggering a stronger process of aromatization. This means that a big part of injected or swallowed testosterone is converted into estrogens, causing serious side effects like bitch tits, or also called gyno.

Each system has different number of aromatase enzymes. The higher is their number, the bigger is the percentage of testosterone who get into estrogen. Thereby, persons with big volume of aromatase enzymes can experience serious health issues even taking anabolic steroids even in smallest doses. Also, this group of bodybuilders have always to pay a bigger attention to antiestrogens drugs when going throughout a cycle.

Why our system has such a categorical reaction to high amounts of testosterone?

Normally a man body produce about 7 mg of testosterone per day. This is a quite modest dose, which not leads to massive muscle gains. Even try naturally, this level will increase but  you will need to put great efforts and much time on this. And efforts doesn’t mean to work hard in the gym only, but also to keep a close eyes to your nutritional diet and rest time.

It is more easier and convenient to get the testosterone level higher by taking steroids. Usually, one dose of steroid is at least 100 mg and higher. This means that suddenly high amounts of testosterone get into body, causing a serious hormonal disbalance.Our body react and try to keep a balance, and begin to convert the surplus of testosterone into estrogen.

So, the answer is that our body is accustomed to a certain amount of testosterone produced daily. It always keep a balance, that’s  why when big doses of synthetic testosterone enters the body it turns it into estrogens. Increased level of estrogen in the system has serious side effects that have to be carefully monitored.

Estrogen has not to be seen as something bad. It has very specific functions in the body like increasing the bone mass, improve libido and greatly add muscle mass if combined with testosterone steroid, for example. Estrogen is a natural steroid, which directly participate in the muscle building process. Along with this, it makes the body to use glucose in a better way, which definitely reduce the recovery period. Being  back in the gym as soon as possible and full of energy and with no soreness is the thing that every bodybuilder want. And estrogen has good influence on all this.

But it have to be kept in normal limits. When it goes too high, serious side effects may occur as gynecomastia, weakness of immunity, and cholesterol issues. There are at least five types of antiestrogens recommended for use during post cycle therapy to reduce estrogenic activity in the body.

Antiestrogens drugs:

Arimidex(Anastrozole)

Clomid (Clomiphene Citrate)

Femara(Letrozole)

HCG (Human Chorionic Gonadotropin)

Nolvadex

We can not say about these drugs that are very expensive as they were few years ago when 1 mg pill of brand name of Arimidex was sold with ten dollars. Nowadays the steroid market is much diversified, and you can find the same product at a very good price. Especially if you are not looking for brand names, and are ready to buy those produced by underground labs.

What are the most aromatizing steroids

All steroids aromatase. This is the most important detail every person looking to get bigger have to bear in mind. But the way they do it differ in some degree. That’s why we can talk about most and less aromatizing steroids, but not about the concept of non aromatization at all. Also, there are individual characteristics as high number of aromatase enzymes in the body, which can turn a low aromatizing steroid into one very estrogenic.

Over the years of experience it was observed that several anabolic steroids induce a greater estrogenic activity when area administered.

Top 4 most aromatizing steroids:

-Dianabol;

-Anadrol;

-Testostosterone;

-Deca

Both forms of Dbol, liquid and pills, have a high estrogenic activity. The same thing can be said about esters of testosterone. It is tremendously to run a proper post cycle therapy with recommended antiestrogens when stacking two or more steroids from the above list. Do it because these steroids are in most cases associated with gyno development.

Water retention is in another unwanted side effects caused by aromatization. Water retention means that you body hold more water, making you look swallowed especially on face aria. Also, it cause in man fat deposition along the waist. The lower is estrogenic activity in the body while running a cycle, the less water your body retain. In other words, in the end of steroid cycle you will have more lean muscle mass gains, instead of such unwanted fat. Antiestrogens are at great importance in this case, so make sure you have them included in your steroid cycle plan.

Considerations

Aromatization is the process during which the surplus of testosterone is turned into estrogens. It comes as a result of body tendency to keep an overall balance. Estrogen in normal limits is very beneficial for body since it improves libido, increase bone mass and makes the muscles get bigger especially if mixed with a synthetic steroid like testosterone. But when high amounts of testosterone enters the body, the estrogen level goes high too, causing serious health problems like gynecomastia, weak immunity and cholesterol changes.

Most of bodybuilders want a non-aromatizing steroid at all, this being unreal. Since all steroids more or less are aromatizing. So, the best would be mention low and high aromatizing steroids. The number of aromatase enzymes in the body have a great importance, the higher is their number the more testosterone into converted into estrogen. Thereby, even a low aromatizing steroid can be quite powerful for such a person.

Prostate cancer and steroids

The human organism is, at birth at least, a well rounded, timed and compact machine, that can function in all conditions on the planet, more or less. The evolution of man has seen to it that the body and organism of man are changed only minimally. We are on top of the food chain in this world, and have no natural enemies, in order to restore balance in the universe Mother Nature has made us susceptible to various types of sicknesses, diseases, viruses etc.

Of course, being as intelligent as we are, the human race has invented medicines for the vast majority of health issues that have been troubling us for many years. That is to say that humans are still yet to find a cure for some of the most dangerous and stubborn sicknesses that have ever existed-HIV, AIDS, cancer etc.

Take cancer, for example: it’s been around for years but no one seems to have been able to find the solution for it. When it strikes, it strikes hard and leaves very little chance of recovery. It can appear almost anywhere in the body, but in the case of cancer location makes no difference-whether it’s:
• Lung
• Stomach
• Tongue
• Throat or
• Prostate- it rarely goes away.

The paradox
Persistent as they are, humans have been trying to find the answer but all of the efforts seem to have been in vain. If you look at prostate cancer-the common medical practice states that, depending on the current state and progression level of the cancer, a prostate intervention is what is needed (in the majority of cases).

However, in recent times it was noticed that androgen therapy has, contrary to popular belief and practice, resulted in an improvement with androgen deficiency symptoms and concomitant prostate disease. What’s more, it is unexplainable how or why the current prostate cancer treatments, such as early discovery and prostate cancer screening, have come to become the common ways of treating prostate cancer, especially since there is no evidence or indication whatsoever in medical literature that support the claim that androgens worsen or even cause prostate disease in the first place.

The eye-opener
In recent experiments and analysis, it was demonstrated that PSA testing (Prostate Specific Antigen) and DRE screening (Digital Rectal Exam) do not significantly reduce prostate cancer rate of death. Furthermore, if PSA and DRE screening results lead to a false finding, which causes patients to receive a surgical procedure that is quite significant-the consequence is a sizeable screening burden. Also, it is noticeable that patients with prostate cancer are receiving a considerable amount of over-treatment simply because prostate cancer screening and also many treatments that follow are so widespread and urgent.

Another type of therapy for prostate cancer that is being used against reason is the androgen ablation therapy-it’s very expensive. The reasons why it’s not very cost effective are primarily the lack of beneficial and usable results, the contrasting effects that cannot be avoided and must be endured, and the considerable costs of the therapy itself.

The solution
Since most anabolic steroids are known to increase testosterone levels in the body, testosterone therapy can potentially be used to improve many signs and recognized symptoms of prostate cancer, and ones that have to do with the deficiency of testosterone in particular. Testosterone therapy can be linked to many positive effects for prostate cancer treatment, unlike androgen deprivation therapy (ADT), for example, which is known to cause the exact opposite effect than that of the testosterone therapy.

The summary
The original and commonly used prostate cancer treatment practices have never been based on appropriate and sufficient data. The true power of evidence based medicine is depicted in the recent realization that the common practices are not only inadequate and ineffective, but also that new and until now untested methods of treatment, such as increasing patients’ testosterone levels, are the way to go in the battle with prostate cancer.

What Luteinizing hormone values tells about natural testosterone production?

LH is an important hormone produced by the pituitary gland for both men and women. In women, it works as part of the menstrual cycle. In men it serves to maintain and produce testosterone and sperm. It is important to stay within a normal range of secretion in order to keep these body functions working correctly and to ensure the general health of your pituitary gland.

To check secretion levels you can request a blood test. Before you go, be aware that tests results may vary, and getting different results even minutes apart is quite normal. Many people become concerned with the differing levels of normal, as they want to be high normal in their levels of testosterone as opposed to low normal.

While high normal is more effective for your body, low normal is not necessarily bad, especially since levels fluctuate regularly. So do not be surprised if your LH levels vary while your levels of testosterone remain consistent.

The true value of measuring LH using a single measure test

It’s a known truth that LH levels can change from minute to minute. This makes small changes in daily production nearly undetectable through testing. An example from another article (source below) gives a comparison of the LH test represented by judging a better hitter in baseball on one hit.

Will the player who has hit better all season necessarily win? No, but that’s why batting averages are made up of every single at-bat. We must think of LH in the same way. The whole (being at a normal level) is more important than the individual highs and lows within normal.

A variable better suited for that kind of test would be something like “Who has blue eyes” or “Who is younger”. Variables like age and eye color do not change. The nature at which the LH changes makes a single measure much less useful in determining daily levels.,

Why the test is still important

While the test cannot give precise information on miniscule daily rises and falls in LH levels, what it can do is indicate when you are dangerously low.

The test will be able to tell you when your pituitary gland is about to go into hypopituitarism. Considering the range of things controlled by your pituitary gland, such as the thyroid, adrenal gland, ovaries, testes, and kidneys, it important to know if you are below average.

The symptoms of hypopituitarism include abdominal pain, fatigue, loss of body hair, shortened height (if during a growth spurt), vision issues, and weight loss, among others. The test is not made to worry about being high or low normal, but it can keep you safe from larger issues.

What can be done if you’re still wanting higher levels of LH?

The problem with recommending drugs to increase levels of a hormone that is hard to measure is that we really cannot gauge the effectiveness of the drug. Some have tried a DAA supplement regimen, but you’ll really only benefit from that if you are consistently low normal. Since we cannot tell how close to a blood peak each test is, worrying about these levels is unnecessary unless your levels are below average.

As long as your LH and testosterone both read some kind of normal, there is no need for worry. But if you’ve got it in your head that you need some kind of measure, the best you can do it measure how the DAA is affecting your testosterone.

Liver damage while on oral steroids

Steroids consumption is associated with a range of side effects, but when it comes to oral steroids liver damaging is the most common. For this main reason, most of steroid users advice to use injectables instead of orals which bedevil the good activity of liver.

In spite of this, oral steroids continue to be largely used by people worldwide. How this can be explained? First of all, injectable steroids can be detected in the blood long time after ending a steroid cycle. In case of orals, traces can be found few weeks after the last ingested pill. It may seem a long time too, but in compare with injectables this frame of time is quite shorter.

On the other hand, there are individuals who fear needles and will do all to avoid dealing with them. In this case, oral injectable is going to be used to replace the gains injectable can cause in human body. Oral steroids are more convenient to use, but are while less effective than injectable.

How is liver damaged while running oral steroid cycle?

Liver is one of the most important organ in human as that if it shuts down we have only 2-3 days to live.  It’s the “cleanser” of  the body, helping to get rid of toxins. Fortunately for us, liver has the capacity to regenerate and be functional even when 75% of it is damaged.

All 17A oral steroids are modified in a way to avoid degradation in the liver and be able to get in the blood. These kinds of steroids are toxic to liver because they inhibit the excretory function of the liver. Likewise, liver can get rid of toxic and they accumulate in the body. Known as cholestasis this is the most common disease caused by 7aa oral steroids are blamed for.

If no action is taken then after a while this disease worsens and may turn into cirrhosis, a stage where the activity begins to slow down. Worth to be mentioned cholestasis is not a lethal disease and is reversible if needed measures are taken on time. The best is to avoid getting to this stage at all, as ideal is to keep your liver safe instead of trying to treat.

The things get worse when two 17A oral steroids are taken concomitantly. Never admit this mistake. Always try to cycle an oral steroid along with an injectable one, this being the smart way of using steroids.

What are the most liver toxic oral steroids?

Don’t put all oral steroids in the same light as not all of them are liver toxic. Some of them are more toxic than others, while a minority has no bad influence on liver at all.

Top most liver toxic oral steroids are:

Superdrol

Dymethazine

Halodrol

Epistane

DHEA

Epiandrosterone

The more potent is the steroid, the higher is the toxicity level it carries on. Therefore, avoid using a powerful oral steroid when looking for fast and impressive muscle gains.

Top of less liver toxic oral steroids:

Winstrol,

Dianabol,

Anadrol.

So, only 17-aa steroids are liver toxic, while all other steroid have minor to no influence at all. A good idea is to stack a 17aa steroid with a non one in order to keep your liver functional while enjoying noticeable gains in muscle mass.

Symptoms of a damaged liver

When your liver function is perturbed because of oral steroid use there are series of signs that you have to worry about. Pay a close attention to your overall feeling when running a steroid cycle to be able to prevent any disease before it will to late.

Here are some of signs that should alarm you when taking orals:

-Lowered appetite;

-Fever associated with nausea (many take it as a cold , but it is not);

-Itchiness;

-Yellowish skin or eyes;

Whenever one of these signs occurs is time to take a break and revise what you are doing wrong. The earlier you acknowledge what happens in your body and give a hand of help, the higher chances to pass through a cycle with your liver function untouched.

The best would be not to wait for these signs, but simply take enzymes before and after steroid cycle. Few weeks later after the cycle is finished repeat the tests and see how it shows. This way you will have a closer look on your liver situation.

Products that help keep liver health while on steroids

As we said is better to prevent than to treat. A range of supplements available online are able to ensure a proper function of liver while taking 17aa steroids. LIV 52 and Milk Thistle, Essentiale  are just few of them, while a simple search on Google would list you a  longer list. Whatever you choose, make sure you have one of these supplements in your cycle.

If you already have liver problems than taking 17aa steroid is a bad idea. Thier use will worsen your condition so that it can turn into something irreversible. Go with injectable in this case or use non-17 aa anabolics.

Protect your liver before it is too late. Make sure your liver is 100% health before getting involves in a 17aa steroid cycle and make sure you add in some supplements able to help you liver cope with bad effects of steroids. Do you tests and keep an eye on signs which talks about a liver problem.

Deca Durabolin and recovery of testosterone production

Do you know Deca Durabolin is also known as Nandrolone Decanoate? Yes, it is an inject-able anabolic steroid. It is the most common and popular form of Nandrolone. Due to the attachment of the Decanoate to the Nandrolone the release times as well as the half life of the steroid can be spread out for more convenience in injections.

While at first, it saw many medical uses, the modern FDA cut back its uses to treating anemic patients, HIV/AIDS patients, and any others who were losing muscle mass due to their condition. It is still widely available in the US, despite cessations and bans of many other steroids.

The Benefits of Taking Deca Durabolin

Deca Durabolin is considered mild in comparison to other anabolic steroids on the issue of side effects. Watch this video to see Deca benefits over one of the most powerful steroids- Tren. Over years of studies, it does not seem to exhibit the same rate of the usual side effects everyone associates with steroids, such as hair loss, aggression, and increases in blood pressure and severe changes in lipids, kidney functions and liver values. This makes it a very popular choice for many steroid users. Despite its popularity for the lack of side effects, it has one major drawback.

Deca Durabolin and recovery of testosterone productionDeca Dick: The Side Effect that Really Matters

One of the well known side effects of steroid use is an effect on testosterone levels. Different types of steroids result in different levels of decrease in production of testosterone. Deca Durabolin is one of the most powerful steroids in use, and thus it creates a serious and noticeable decrease in testosterone levels.

“Deca Dick” has become commonly used slang to describe those on the steroid with Erectile Dysfunction. It is a hot topic in every forum and unfortunately for Deca Durabolin users, not only is it incredibly potent, but also has a higher recovery time for the user to recover to regular testosterone levels.

Is there more to low testosterone than just ED?

Most people know that lower testosterone levels will decrease a man’s libido. But there are a number of other risks and side effects of low testosterone levels that are often forgotten in the wake of erectile dysfunction. Some of these side effects include increased body fat, fragile bones, swelling and tenderness of breast tissue, hot flashes, and increased fatigue.

It can also affect sleep cycles and cause depression. These issues, which could develop into more serious problems, should be kept in mind along with ED when considering the benefits of Post Cycle Therapy.

The Benefits and Importance of Post Cycle Therapy (PCT)

Post Cycle Therapy can be crucial to increasing testosterone levels at a more desirable rate. PCT is much more than just recovering testosterone. PCT helps to keep your entire endocrine system healthy. In the early days of steroids in the 50’s, 60’s, and 70’s not much was known about their effects on the endocrine system. It wasn’t until the 80’s or 90’s that doctors and scientists realized the extent to which steroids affected the Hypothalamic Pituitary Testicular Axis (HPTA). PCT was born out of this revelation, and has been encouraged ever since.

The Results of Skipping PCT

While a body can usually rebalance itself in 1 to 4 months that could be counteractive to the benefits of the steroid cycle it as the imbalance has enough time to affect the body in multiple ways. Decreasing the time it takes the body to regain testosterone levels (which can be as low as 75% decrease in Deca Durabolin users) can ensure the health of the endocrine system as well as the avoidance of other symptoms that come with below average testosterone levels.

Conclusion

Deca can indeed cause you huge muscle growth, but wrong use can also lead to serious side effects. In order to stay safe and enjoy great results, educate yourself about Deca proper usage, side effects, stacks, recommendations and things to avoid.  PCT is just one of them and play a big role.

Growth hormone deficiency in children

Growth hormone deficiency means the pituitary gland does not make enough growth hormone.


The pituitary gland is located at the base of the brain. This gland controls the body’s balance of hormones. It also makes growth hormone. This hormone causes a child to grow.
Growth hormone deficiency may be present at birth (congenital). Or it may be the result of medical condition. Severe brain injury may also cause growth hormone deficiency.
Children with physical defects of the face and skull, such as cleft lip or cleft palate, may have decreased growth hormone levels.
Most of the time, the cause of growth hormone deficiency is unknown.

Symptoms
Slow growth may first be noticed in infancy and continue through childhood. The pediatrician will usually draw the child's growth curve on a growth chart. Children with growth hormone deficiency have a slow or flat rate of growth. The slow growth may not show up until a child is 2 or 3 years old.
The child will be much shorter than most children of the same age and gender. The child will still have normal body proportions though body build may be chubby. Often the child’s face looks younger than children of the same age. The child will usually have normal intelligence.
In older children, puberty may come late or may not come at all, depending on the cause.

Exams and Tests
A physical examination, including weight, height, and body proportions, will show signs of slowed growth rate. The child will not follow the normal growth curves.
Hand x-ray can determine bone age. Normally, the size and shape of bones change as a person grows. These changes can be seen on an x-ray and usually follow a pattern as a child grows older.
Testing is usually done after the  pediatrician has looked into other causes of poor growth. Tests that may be done include:
Growth hormone causes the body to make insulin-like growth factor (IGF1) and insulin-like growth factor binding protein 3 (IGFBP3). Tests can measure these growth factors.Accurate growth hormone deficiency testings involves a stimulation test. This test takes several hours.
MRI of the head can show the hypothalamus and pituitary glands.
Tests to measure other hormone levels may be done because lack of growth hormone may not be the only problem.

Treatment
Treatment involves growth hormone shots (injections) given at home. The shots are usually given once a day. Older children can often learn how to give themselves the shot.
Treatment with growth hormone is long-term, often several years. During this time, the child needs to be seen regularly by the doctor to ensure treatment is working and to change the dosage of the medicine if needed.
Serious side effects of growth hormone treatment are rare. Common side effects include:

    Headache
    Fluid retention
    Muscle and joint aches
    Slippage of the bones at the hip

The earlier the condition is treated, the better the chance that a child will grow to near-normal adult height. Many children gain 4 or more inches over the first year and 3 or more inches during the next 2 years. The rate of growth then slowly decreases.

The Benefits of Human Growth Hormone

Human Growth Hormone, commonly known as HGH is a protein based peptide hormone of incredible anabolic properties and functions found in all human beings and essential for a host of functions within the human body. While HGH therapy has existed for many years safe and effective administration was not available until the mid-1980’s when synthetic versions first hit the shelf; prior to this period the only way one could obtain Human Growth Hormone for therapy was from direct extraction from the pituitary of cadavers; an often dangerous and unsanitary practice. However, by the late 1990’s and early 2000’s HGH in a biosynthetic form was now highly available and since that time it has been one of the most sought after hormones in both hormone replacement therapy and the world of performance enhancement. Commonly referred to as the fountain of youth hormone HGH has been shown to produce enumerable traits in preserving youth and vigor as well as muscular development and improved metabolic efficiency. Even as Human Growth Hormone remains one of the more expensive hormones to purchase, as its benefits are great and its safety record is nearly perfect it remains highly popular despite the price one may pay.

The Benefits of Human Growth Hormone:
To understand the benefits of Human Growth Hormone we can largely see them by simply understanding its basic function(s) as discussed above; however, unfortunately as we age such benefits began to fall short as natural HGH production declines as we age and often at a rapid rate. For this reason more and more people the world over, both men and women have begun supplementing with biosynthetic Human Growth Hormone in an effort to avoid such a crash, as well as many athletes from baseball to football, track & field to bodybuilders and power lifters, gym rats and everything in-between. While therapeutic doses aimed at slowing down the signs of aging are common, as it pertains to the athletic world and performance enhancing doses are commonly much higher as the idea here is not to simply provide adequate levels but to surpass them so that the benefits can become further enhanced.

Through the use of supplemental Human Growth Hormone the individual can expect to reap the rewards of several beneficial applications and they apply universally to all who use it regardless of purpose; however, the rate of acceleration and the total end will largely vary from one to the next based on dosing and the coupling of anabolic androgenic steroids. Anabolic steroid use is very common with HGH use in the athletic world as both act in a means to work together enhancing the effects of each.

Those who administer biosynthetic HGH can largely expect a host of beneficial attributes such as muscle tissue growth, higher metabolic rates, a leaner and tighter physique, increased recovery within the body, increased bone, joint and tendon strength, healthier looking skin, as well as increased energy. While these are largely the physical attributes in their general sense, Human Growth Hormone goes far beyond the direct physical and holds other very important traits as well. Those who supplement with Human Growth Hormone will find they possess a greater clarity of thought and focus as well as enhanced moods overall as HGH can largely stave off such problems as depression. If levels of HGH in the body fall below optimal range each one of the positive benefits just discussed begins to decline as well; this is why as you can see proper levels are very important. In that same light, as levels increase beyond natural production each and every beneficial attribute is enhanced to degrees previously deemed unimaginable.

Real Human Growth Hormone:
As is common in the world of anabolic steroids, as HGH is not an anabolic steroid in any shape or form, like many steroids it is often counterfeited, so much so it is without question the most commonly counterfeited hormone in the performance enhancing world when purchased on the black market. Moreover, in recent years due to HGH popularity increasing many legal peptide fragments have hit the shelves; these fragments are often a partial Human Growth Hormone medication but this is like buying half a sandwich and one that won’t digest properly. While these fragment peptides are generally safe they are also generally worthless. When you are looking to obtain true blue Human Growth Hormone stay away from the generic black market brands and stick with true manufactures of the hormone such as Humatrope, Saizen, Serostim and Nutropin to name a few.

Human Growth Hormone Cycles and Doses:
Because it possesses such a high safety rating Human Growth Hormone can be used indefinitely; there is no max time frame in-which we must hold to. However, as beneficial as the hormone is it will take a long time to see such benefits; a few weeks of HGH therapy is a waste of money and a complete waste of good HGH. To reap a true benefit 16 weeks is generally the minimal amount of time you’ll want to supplement with HGH with 6 months being far more optimal. While this can be expensive consider this; the effects of Human Growth Hormone are largely permanent and that is worth noting.

Depending on your purpose the dose may vary from person to person. Human Growth Hormone is normally dosed in International Units or IU and as such, in therapeutic cases 1iu per day is very common place among both men and women with it occasionally going up to 2iu per day. However, for the performance enhancer, as it pertains to women 2iu per day will often prove to be perfect; while 2iu per day will provide many beneficial effects for men, notably fat-loss, to receive a full anabolic effect 4iu will prove to necessarily be optimal. While 4iu is highly beneficial and generally safe, the individual will not notice much difference in doses that are in the 5-6iu range; it is not until we get into the double digit doses that effects are greatly enhanced beyond the 4iu mark. However, although the side-effects of HGH are rare, when we delve into these very high doses they are almost guaranteed.