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Wednesday, April 15, 2015

Using Clomid and HCG for Post Cycle Therapy

Why Bodybuilders Use Clomid
Clomid is a generic name for Clomiphene Citrate and is a synthetic estrogen. It is prescribed medically to aid ovulation in low fertility females. Another generic name is Serophene.

Most anabolic steroids, especially the androgens, cause inhibition of the body's own testosterone production. When a bodybuilder comes off a steroid cycle, natural testosterone production is zero and the levels of the steroids taken in the blood are diminishing. This leaves the ratios of catabolic : anabolic hormones in the blood high, hence the body is in a state of catabolism, and, as a result, much of the muscle tissue that was gained on the cycle is now going to be lost.

Clomid stimulates the hypothalamus to, in turn stimulant the anterior pituitary gland (aka hypophysis) to release gonadotrophic hormones. The gonadotrophic hormones are follicle stimulating hormone (FSH) and luteinizing hormone (LH - aka interstitial cell stimulating hormone (ICSH)). FSH stimulates the testes to produce more testosterone, and LH stimulates them to secrete more testosterone. This feedback mechanism is known as the hypothalamic-pituitary-testes axis (HPTA), and results in an increase of the body's own testosterone production and blood levels rise, to, in part, compensate for the diminishing levels of exogenous steroids. This is vital to minimise post cycle muscle losses.

Not all steroids do cause shut down of the feedback mechanism. Everyone is different and you must also take into account how long you have been using a certain steroid and at what dose in order to determine if you need Clomid or not.

Clomid also works as an anti-estrogen. As it's a weak synthetic estrogen, it binds to estrogen receptors on cells blocking them to estrogen in the blood. This minimises the negative effects like gynecomastia and water retention that may be a result of estrogen that has aromatised from testosterone.

It's effect as an anti-estrogen are quite weak though, and it should not be relied upon if you are going to be using androgenic steroids that aromatise at a rapid rate, or if you are pre-disposed to gynecomastia. Arimidex and Nolvadex (Tamoxifen) are far more effective anti-estrogens.

Important note: Clomid does not, as is often thought, stimulate the release of natural testosterone, but rather works at reducing the estrogenic inhibition caused by the steroid cycle. It does this in a similar manner to the way it and Nolvadex block estrogen receptors in nipples to combat gyno development, i.e. by blocking the estrogen receptors in the hypothalamus and pituitary thus reducing the inhibition from the elevated estrogen. This allows LH levels to return to normal, or even above normal levels, and in turn, natural testosterone levels to also normalise.

Inhibition of the HPTA is caused by either elevated androgen, estrogen or progesterone levels. On cessation of the steroid cycle, androgen levels begin to fall and Clomid dosing is normally commenced according to the half-life of the longest acting drug in the system (see below).

This may also explain the reason individuals often find post-deca recovery more difficult, as the progesterone presence is untouched by the Clomid. We know that Clomid and Nolvadex (being very similar chemically) are both ineffective with regard to reducing progesterone related gyno, so it is reasonable to assume that Clomid has little effect against progesterone levels.

Clomid During A Cycle
When we use anabolic steroids, the level of androgens in the body rises causing the androgen receptors to become more highly activated, and through the HPTA, a signal tells our testes to stop producing testosterone. During a cycle the body has far higher than normal levels of androgens and, as long as this level is high enough, Clomid will not help to keep natural testosterone production up. It will be almost all but completely shut off, in theory.

Some heavy androgen users, however, do advocate a small burst of Clomid mid-cycle, though it must be hard for them to say if it really of any benefit, due to the amount of gear they are using. Therefore, the only purpose of Clomid during a cycle is as an anti-estrogen.


When To Start Clomid
The correct time to commence Clomid depends on the type and cycle of steroids you have been using. Different steroids have different half-lifes (indicates the time a substance diminishes in blood), and Clomid administration should be taken accordingly.

As we have seen above, Clomid taken when androgen levels in our blood are still high will be a waste. It is crucial to wait for androgen levels to fall before implementing our Clomid therapy. However, if taken too late we could possibly lose gains.

The list below determines when you should start Clomid. Select from the list any steroids you've used in your cycle and whichever one has the latest starting point is the time to commence Clomid. For example, if Dianabol, Sustanon and Winstrol were cycled, the time for administering Clomid should be 3 weeks post cycle, as Sustanon remains active in the body for the longest period of time.

Steroid                               Time after last administration  Length of Clomid Cycle
Anadrol50/Anapolan50:                     8 - 12 hours                                 3 weeks
Deca durabolan:                                 3 weeks                                       4 weeks
Dianabol:                                            4 - 8 hours                                   3 weeks
Equipoise:                                           17 - 21 days                                 3 weeks
Finajet/Trenbolone:                            3 days                                          3 weeks
Primabolan depot:                              0 - 14 days                                   2 weeks
Sustanon:                                            3 weeks                                       3 weeks
Testosterone Cypionate:                     2 weeks                                       3 weeks
Testosterone Enanthate/Testaviron:   2 weeks                                       3 weeks
Testosterone Propionate:                    3 days                                         3 weeks
Testosterone Suspension:                    4 - 8 hours                                 2-3 weeks
Winstrol                                               8 - 12 hours                               2-3 weeks

How To Take Clomid
Clomid has a long half-life (possibly 5 days), so there is no need to split up doses throughout the day. If Sustanon has been used and Clomid is commenced 3 weeks after the last injection, I would estimate that androgen levels are low enough to start sending the correct signals. If androgen levels are still a little high, we need to start at a high enough amount that will work or help, even if androgen levels are still a little high. Try 300mg on day 1; then use 100mg for the next 10 days; followed by 50mg for 10 days.

Using HCG
It is our opinion that HCG is probably one of the most misunderstood and misused compounds in bodybuilding. Hopefully this information will go some way towards rectifying that for the members of MuscleTalk. HCG stands for Human Chorionic Gonadotrophin and is not a steroid, but a natural peptide hormone which develops in the placenta of pregnant women during pregnancy to controls the mother's hormones. (Incidentally, this is the reason you may hear of people testing for growth hormone (HGH) with a pregnancy testing kit - If their HGH shows 'pregnant', they've been ripped-off with cheaper HCG - but we digress slightly).

Its action in the male body is like that of LH, stimulating the Leydig cells in the testes to produce testosterone even in the absence of endogenous LH. HCG is therefore used during longer or heavier steroid cycles to maintain testicular size and condition, or to bring atrophied (shrunken) testicles back up to their original condition in preparation for post-cycle Clomid therapy. This process is necessary because atrophied testicles produce reduced levels of natural testosterone, this situation should be rectified prior to post-cycle Clomid therapy.

HCG administration post-cycle is common practice among bodybuilders in the belief that it will aid the natural testosterone recovery, but this theory is unfounded and also counterproductive. The rapid rise in both testosterone, and thus estrogen due to aromatisation, from the administration of HCG causes further inhibition of the HPTA (Hypothalamic/Pituitary/Testicular Axis - feedback loop discussed above); this actually worsens the recovery situation. HCG does not restore the natural testosterone production.

The typically observed dosing of 2000 to 5000IU every 4 to 5 days causes such an increase in estrogen levels via aromatisation of the natural testosterone that this has been responsible for many cases of gynecomastia.

From the above discussion it is clear that HCG is best used during a cycle, either to:

1) Avoid testicular atrophy, or
2) Rectify the problem of an existing testicular atrophy.

Doses of HCG
Smaller doses, more frequently during a cycle will give best overall results with least unwanted side effects. Somewhere between 500iu and 1000iu per day would be best over about a two-week period. These doses are sufficient to avoid/rectify testicular atrophy without increasing estrogen levels too dramatically and risking gynecomastia. This dosing schedule also avoids the risk of permanently down-regulating the LH receptors in the testes.

Presentation and Administration of HCG
Synthetic HCG is often known as Pregnyl (generic name) and is available in 2500iu and 5000iu (not ideal for the above doses!). Administration of the compound is either by intra-muscular or subcutaneous injection. It comes as a powder which needs to be mixed with the sterile water. The powder is temperature-sensitive prior to mixing and should not be exposed to direct heat. After mixing, it should be kept refrigerated and used within a few weeks - though there are sterility issues which need to be considered after mixing.

Wednesday, March 11, 2015

What to Do When an Illness Interrupts a Steroid Cycle

What to do if you get sick during a cycle and can’t train properly or your body obviously just doesn’t have the energy to gain?

Beter not change your plans when an illness likely will have you down for only a few days, but to end the cycle if it’s likely to be about a week or more.

Ending a cycle early allows the next cycle to start earlier, completely compensating for the change in schedule. It’s not really a loss at all. You could start the next cycle as soon as you’ve completed the same number of weeks “off” that you had been “on,” or if you wish to be more conservative, twice that time. This will be much sooner than would be the case if you’d continued the cycle despite the illness. You won’t be setting yourself back overall.

If your testosterone was good before the cycle and the cycle length has been fairly short, such as 8 weeks or less, in most cases recovery will be good simply from using a SERM as PCT. The most common choices are Clomid or Nolvadex.

However, if and only if you suspect recovery of natural testosterone might be slow, then use in PCT either HCG or low-dose testosterone, such as 100 mg/week.

This is because we don’t want the immune system adversely affected by testosterone dropping too low.

Intermediate steroid doses – not enough for real gains, yet too much for recovery of the HPTA – are a waste of your time. Either be on-cycle, or in recovery. Whatever muscle loss may occur while ill will be easily recovered on regaining health. Again, ending steroid use earlier will allow restarting earlier, and this will be much more productive than trying to avoid losses while ill.

In short, optimize your usage. And using anabolic steroids while down and unable to train is not optimizing usage.

Tuesday, February 24, 2015

Recovery of Testosterone Production and Deca Durabolin

Do you know Deca Durabolin is also known as Nandrolone Decanoate? Yes, it is an inject-able anabolic steroid. It is the most common and popular form of Nandrolone. Due to the attachment of the Decanoate to the Nandrolone the release times as well as the half life of the steroid can be spread out for more convenience in injections.

While at first, it saw many medical uses, the modern FDA cut back its uses to treating anemic patients, HIV/AIDS patients, and any others who were losing muscle mass due to their condition. It is still widely available in the US, despite cessations and bans of many other steroids.

The Benefits of Taking Deca Durabolin
Deca Durabolin is considered mild in comparison to other anabolic steroids on the issue of side effects. Watch this video to see Deca benefits over one of the most powerful steroids- Tren.
Over years of studies, it does not seem to exhibit the same rate of the usual side effects everyone associates with steroids, such as hair loss, aggression, and increases in blood pressure and severe changes in lipids, kidney functions and liver values. This makes it a very popular choice for many steroid users. Despite its popularity for the lack of side effects, it has one major drawback.

The Side Effect that Really Matters
One of the well known side effects of steroid use is an effect on testosterone levels. Different types of steroids result in different levels of decrease in production of testosterone. Deca Durabolin is one of the most powerful steroids in use, and thus it creates a serious and noticeable decrease in testosterone levels.
“Deca Dick” has become commonly used slang to describe those on the steroid with Erectile Dysfunction. It is a hot topic in every forum and unfortunately for Deca Durabolin users, not only is it incredibly potent, but also has a higher recovery time for the user to recover to regular testosterone levels.

Is there more to low testosterone than just ED?
Most people know that lower testosterone levels will decrease a man’s libido. But there are a number of other risks and side effects of low testosterone levels that are often forgotten in the wake of erectile dysfunction. Some of these side effects include increased body fat, fragile bones, swelling and tenderness of breast tissue, hot flashes, and increased fatigue.
It can also affect sleep cycles and cause depression. These issues, which could develop into more serious problems, should be kept in mind along with ED when considering the benefits of Post Cycle Therapy.

The Benefits and Importance of Post Cycle Therapy (PCT)
Post Cycle Therapy can be crucial to increasing testosterone levels at a more desirable rate. PCT is much more than just recovering testosterone. PCT helps to keep your entire endocrine system healthy. In the early days of steroids in the 50’s, 60’s, and 70’s not much was known about their effects on the endocrine system. It wasn’t until the 80’s or 90’s that doctors and scientists realized the extent to which steroids affected the Hypothalamic Pituitary Testicular Axis (HPTA). PCT was born out of this revelation, and has been encouraged ever since.

The Results of Skipping PCT
While a body can usually rebalance itself in 1 to 4 months that could be counteractive to the benefits of the steroid cycle it as the imbalance has enough time to affect the body in multiple ways. Decreasing the time it takes the body to regain testosterone levels (which can be as low as 75% decrease in Deca Durabolin users) can ensure the health of the endocrine system as well as the avoidance of other symptoms that come with below average testosterone levels.

Conclusion
Deca can indeed cause you huge muscle growth, but wrong use can also lead to serious side effects. In order to stay safe and enjoy great results, educate yourself about Deca proper usage, side effects, stacks, recommendations and things to avoid.  PCT is just one of them and play a big role.

Friday, December 19, 2014

How to protect liver during steroid cycle

Steroids are blamed for many negative effects on human body, one of them being liver toxicity. But not all of them are responsible for damaging the liver. All alkylated anabolic steroids are proved to have bad influence in liver function. What are these steroids? All oral anabolics with the most common of them in the top: Dianabol, Anadrol, Anavar and of course Winstrol.

Non-alkylated steroids are injectable steroids like Testosterone, Masteron, Equipoise, Deca Durabolin, Primobolan and others. If you want free of liver effects steroids than choose one of this group. This is especially important for those who are susceptible to liver problems.

Liver has the role to clean our body of toxins. Steroids are toxins, hence when they enter the body begin to eliminate them, without letting them get in ten blood. To avoid being breakdown into liver, oral steroids were modified in a way that inhibits the excretory function of the liver. It is not able to eliminate toxins; hence they accumulate in the body causing serious health problems.

We wrote about how oral steroids destroy liver, so will will not detail too much this subject. To read more about it click  on this article “Oral Anabolic Steroids, Liver Enzyme Tests and Liver Function“.

The intend of this post is to show how to break through a steroids cycle keeping your liver fully functional. Read further and find how exactly you can do it.

Use a non-alkylated steroid as base

The use of oral steroids alone is contraindicated. It put a high pressure in the liver and it may cede. Even you have a healthy liver, always stack an injectable with an oral. Such a mix has also a great synergic effect. So that you do not only manage to protect your liver, but also accomplish great results, whether you are bulking or cutting.

The dosage has to be no higher than 350-750mg per week of stack. A higher dosage will inhibit liver function even the gains will be better then you expected. You may get bigger or slimmer, but your liver is goanna be deeply affected. Just to know, individuals can live only 2-3 days if liver function is shut down.

Read this ” Building muscle using therapeutic dosages of steroids to find out how” to understand that staying on minimal dosage still can provide you with nice gains.

Cycle duration has not to exceed 6 weeks. Of course there are many steroid users taking oral anabolics for much longer time without apparently damaging the liver. Acting so is a a big mistake. What they miss is that with every week steroids cause scar tissue which is undetected. They worsen in time as steroids consumption don’t let them heal. The finality is that you get not only with big muscle, but also big scars which put you at risk to develop cancer.

Six weeks are the frame time within the activity of liver is still normal and steroids influence is not devastating. With proper manipulation great results can be achieved even within “short steroid cycle”.  High steroid dosage for long time are too dangerous for your health to risk it.

Choose short steroid cycle over long cyles. Read here why -  The pros of using short steroid cycles

If still want to make your cycle longer, than replacing orals with injectables is a must. For every gram of Winstrol or Anadrol take Testosterone, while Anavar can be replaced with Trenbolone in a 2:3 basis. Search for the injectable which carry the same effects the oral did and make the substitution beginning with the 7th week of cycling.

No bridging between cycles

Alkylated steroids cycles have to be followed by the same amount of time if not more. Allow body time to get back to its normal function. Liver regenerate if time is allowed. And so do hormones and other vital organs.

Don’t know exactly how long the break between cycles should be ? Find here -Time between steroids

It’s common nowadays to not stop taking steroids using bridging. Aside of damaging your liver, such a method is not productive. The more steroids take, the higher resistance body builds to it so that they become inefficient after a period of time. That’s why take breaks and let the body detach from toxins that entered it during time. After a while, you can get back in cycling.

Take supplements to protect liver

Despite of caution steroid use, including liver supplements in your diet is necessary. Lecithin, Liv-52 and Milk Thistle, Essentiale are some products to take in consideration but you are not limited to them. Buy from reliable sources to make sure you ingest high quality products. And this is available for anabolics too.

No alcohol or liver toxic medications

When cycling avoid drinking alcohol at all and be caution to drugs that shows liver toxicity properties. The liver activity is already perturbed, don’t worsen the situation.

Bottom line. Before get involved in oral steroid cycle make sure your liver function is normal. The same do when cycle is over and you are ready for the next one. Throw away the idea of oral cycle if you already have liver issues. It’s not for you. In all other cases keep in mind the above mentioned tricks and liver activity will not be affected in a degree that put your health in danger.

Friday, December 12, 2014

Tren Cough: should you worry about it?

Some trenbolone acetate users who claimed that they have used this drug in the past without any side effects, but they recently suffered of terrible tren cough from the trenbolone acetate on many of the injections used. They also say that the tren cough only lasts about 30 seconds, but they consider it quite severe so that they sometimes wonder whether they are going to survive it or not.

Although they are aware of the fact that the tren cough won’t actually kill them, they feel very bad while having it and therefore are relatively scared for their life’s those few seconds that this tren cough lasts. These users have been wondering what is actually happening to them and what can they do about this.

The trenbolone acetate has an unpleasant and quite unusual property, which makes it be irritating to some of the human tissues. For example, in the case of the tongue, the trenbolone acetate is very spicy.

Also, if by mistake, the user of trenbolone acetate gets a trace of it on the hands, then he shouldn’t handle any potatoes or meat until he washes the trenbolone acetate off thoroughly, as this drug is very irritating to potatoes and meat. This is an important fact which shouldn’t be ignored.

The tissues affected by trenbolone acetate

When used at a very high concentration, the trenbolone acetate is very irritating to the lung tissue. Generally, the blood levels are not at all near to the level that is responsible for producing the tren cough. However, in specific cases, there can happen the following things:

– The individual may introduce a small amount of oil right into a very small blood vessel

- Some trenbolone acetate may enter immediately into the lymphatic system

In any of this two particular cases, the body, especially the lungs, will experience a very high level of trenbolone acetate, which will most likely result in tren cough.

The luck of every injection

Basically, it can be considered that the apparition of the tren cough is only a matter of luck, as far as even in an individual, some injections might determine the tren cough to appear, while some injections might not cause the tren cough to occur.

Another factor that can be considered responsible for the apparition of tren cough is the formulation of the injection. Factors from its formulation that might be considered responsible for the causing of tren cough include the following:

– A higher concentration of trenbolone acetate might cause such problems as the tren cough

- The benzyl alcohol may also increase the risk of the tren cough’s apparition

How to minimize the risk of tren cough apparition

Although no one can actually avoid the tren cough to occur, it is somehow possible to minimize the risk of its apparition. In order to minimize the rate of tren cough, the individual using trenbolone acetate can try doing the following:

– Reduce the dosage to 50mg/mL or to 75mg/mL and it is also preferable to opt for trenbolone acetate without benzyl alcohol

– When opting for the dosage of 50mg/mL, the formulation does need to only contain trenbolone acetate together with vegetable oil or ethyl oleate. In this formulation, the benzyl benzoate is optional

– When opting for the dosage of 75mg/mL, it is important that it contains either benzyl acetate or benzyl benzoate. It is recommended that it contains benzyl benzoate in a concentration of 20%

Conclusion

It is possible that the tren cough occurs with an injection. However, there is nothing that can be done with it, except though it out. The tren cough might seem severe, but it usually ends relatively quickly. Basically, it is gone in less than 30 seconds, in rare cases it can go up to 60 seconds and it very rarely lasts for about 90 seconds.

Friday, December 5, 2014

What is steroid aromatization

When taking steroids, there are number of process that happens in the body. Along with anabolic effect, steroids may cause some serious side effects that every bodybuilder fears of. Most of them are estrogenic issues caused by the strong aromatization.

Bodybuilders search on the internet for low aromatizing steroids or even for those who do not aromatize at all. This is a wrong approach, since all steroids aromatize, but in different degree.

To better understand why all steroids carry the risk of aromatization and how bad it is for your health, you will have to know, first of all, what aromatization means, what cause it and how can be prevented its downsides. Yes, downsides, since generally it is good process for body and you will see in this article why.

Aromatization is not triggered by steroid use. It is a natural process during which testosterone is transformed into estrogen. This process is carried out by a special enzyme in our body called aromatase, thus the whole processed was called aromatization. The main task or aromatization is the synthesis of cholesterol and fats. But it changes when body feels a testosterone boost.

Human body has a very interesting characteristic: it tend to ensure a balance in all it has-muscles, hormones, temperature and others. This stage is known as homeostasis. When big amounts of testosterone enters the body, homeostasis try to put the things in order by triggering a stronger process of aromatization. This means that a big part of injected or swallowed testosterone is converted into estrogens, causing serious side effects like bitch tits, or also called gyno.

Each system has different number of aromatase enzymes. The higher is their number, the bigger is the percentage of testosterone who get into estrogen. Thereby, persons with big volume of aromatase enzymes can experience serious health issues even taking anabolic steroids even in smallest doses. Also, this group of bodybuilders have always to pay a bigger attention to antiestrogens drugs when going throughout a cycle.

Why our system has such a categorical reaction to high amounts of testosterone?

Normally a man body produce about 7 mg of testosterone per day. This is a quite modest dose, which not leads to massive muscle gains. Even try naturally, this level will increase but  you will need to put great efforts and much time on this. And efforts doesn’t mean to work hard in the gym only, but also to keep a close eyes to your nutritional diet and rest time.

It is more easier and convenient to get the testosterone level higher by taking steroids. Usually, one dose of steroid is at least 100 mg and higher. This means that suddenly high amounts of testosterone get into body, causing a serious hormonal disbalance.Our body react and try to keep a balance, and begin to convert the surplus of testosterone into estrogen.

So, the answer is that our body is accustomed to a certain amount of testosterone produced daily. It always keep a balance, that’s  why when big doses of synthetic testosterone enters the body it turns it into estrogens. Increased level of estrogen in the system has serious side effects that have to be carefully monitored.

Estrogen has not to be seen as something bad. It has very specific functions in the body like increasing the bone mass, improve libido and greatly add muscle mass if combined with testosterone steroid, for example. Estrogen is a natural steroid, which directly participate in the muscle building process. Along with this, it makes the body to use glucose in a better way, which definitely reduce the recovery period. Being  back in the gym as soon as possible and full of energy and with no soreness is the thing that every bodybuilder want. And estrogen has good influence on all this.

But it have to be kept in normal limits. When it goes too high, serious side effects may occur as gynecomastia, weakness of immunity, and cholesterol issues. There are at least five types of antiestrogens recommended for use during post cycle therapy to reduce estrogenic activity in the body.

Antiestrogens drugs:

Arimidex(Anastrozole)

Clomid (Clomiphene Citrate)

Femara(Letrozole)

HCG (Human Chorionic Gonadotropin)

Nolvadex

We can not say about these drugs that are very expensive as they were few years ago when 1 mg pill of brand name of Arimidex was sold with ten dollars. Nowadays the steroid market is much diversified, and you can find the same product at a very good price. Especially if you are not looking for brand names, and are ready to buy those produced by underground labs.

What are the most aromatizing steroids

All steroids aromatase. This is the most important detail every person looking to get bigger have to bear in mind. But the way they do it differ in some degree. That’s why we can talk about most and less aromatizing steroids, but not about the concept of non aromatization at all. Also, there are individual characteristics as high number of aromatase enzymes in the body, which can turn a low aromatizing steroid into one very estrogenic.

Over the years of experience it was observed that several anabolic steroids induce a greater estrogenic activity when area administered.

Top 4 most aromatizing steroids:

-Dianabol;

-Anadrol;

-Testostosterone;

-Deca

Both forms of Dbol, liquid and pills, have a high estrogenic activity. The same thing can be said about esters of testosterone. It is tremendously to run a proper post cycle therapy with recommended antiestrogens when stacking two or more steroids from the above list. Do it because these steroids are in most cases associated with gyno development.

Water retention is in another unwanted side effects caused by aromatization. Water retention means that you body hold more water, making you look swallowed especially on face aria. Also, it cause in man fat deposition along the waist. The lower is estrogenic activity in the body while running a cycle, the less water your body retain. In other words, in the end of steroid cycle you will have more lean muscle mass gains, instead of such unwanted fat. Antiestrogens are at great importance in this case, so make sure you have them included in your steroid cycle plan.

Considerations

Aromatization is the process during which the surplus of testosterone is turned into estrogens. It comes as a result of body tendency to keep an overall balance. Estrogen in normal limits is very beneficial for body since it improves libido, increase bone mass and makes the muscles get bigger especially if mixed with a synthetic steroid like testosterone. But when high amounts of testosterone enters the body, the estrogen level goes high too, causing serious health problems like gynecomastia, weak immunity and cholesterol changes.

Most of bodybuilders want a non-aromatizing steroid at all, this being unreal. Since all steroids more or less are aromatizing. So, the best would be mention low and high aromatizing steroids. The number of aromatase enzymes in the body have a great importance, the higher is their number the more testosterone into converted into estrogen. Thereby, even a low aromatizing steroid can be quite powerful for such a person.

Friday, November 28, 2014

Prostate cancer and steroids

The human organism is, at birth at least, a well rounded, timed and compact machine, that can function in all conditions on the planet, more or less. The evolution of man has seen to it that the body and organism of man are changed only minimally. We are on top of the food chain in this world, and have no natural enemies, in order to restore balance in the universe Mother Nature has made us susceptible to various types of sicknesses, diseases, viruses etc.

Of course, being as intelligent as we are, the human race has invented medicines for the vast majority of health issues that have been troubling us for many years. That is to say that humans are still yet to find a cure for some of the most dangerous and stubborn sicknesses that have ever existed-HIV, AIDS, cancer etc.

Take cancer, for example: it’s been around for years but no one seems to have been able to find the solution for it. When it strikes, it strikes hard and leaves very little chance of recovery. It can appear almost anywhere in the body, but in the case of cancer location makes no difference-whether it’s:
• Lung
• Stomach
• Tongue
• Throat or
• Prostate- it rarely goes away.

The paradox
Persistent as they are, humans have been trying to find the answer but all of the efforts seem to have been in vain. If you look at prostate cancer-the common medical practice states that, depending on the current state and progression level of the cancer, a prostate intervention is what is needed (in the majority of cases).

However, in recent times it was noticed that androgen therapy has, contrary to popular belief and practice, resulted in an improvement with androgen deficiency symptoms and concomitant prostate disease. What’s more, it is unexplainable how or why the current prostate cancer treatments, such as early discovery and prostate cancer screening, have come to become the common ways of treating prostate cancer, especially since there is no evidence or indication whatsoever in medical literature that support the claim that androgens worsen or even cause prostate disease in the first place.

The eye-opener
In recent experiments and analysis, it was demonstrated that PSA testing (Prostate Specific Antigen) and DRE screening (Digital Rectal Exam) do not significantly reduce prostate cancer rate of death. Furthermore, if PSA and DRE screening results lead to a false finding, which causes patients to receive a surgical procedure that is quite significant-the consequence is a sizeable screening burden. Also, it is noticeable that patients with prostate cancer are receiving a considerable amount of over-treatment simply because prostate cancer screening and also many treatments that follow are so widespread and urgent.

Another type of therapy for prostate cancer that is being used against reason is the androgen ablation therapy-it’s very expensive. The reasons why it’s not very cost effective are primarily the lack of beneficial and usable results, the contrasting effects that cannot be avoided and must be endured, and the considerable costs of the therapy itself.

The solution
Since most anabolic steroids are known to increase testosterone levels in the body, testosterone therapy can potentially be used to improve many signs and recognized symptoms of prostate cancer, and ones that have to do with the deficiency of testosterone in particular. Testosterone therapy can be linked to many positive effects for prostate cancer treatment, unlike androgen deprivation therapy (ADT), for example, which is known to cause the exact opposite effect than that of the testosterone therapy.

The summary
The original and commonly used prostate cancer treatment practices have never been based on appropriate and sufficient data. The true power of evidence based medicine is depicted in the recent realization that the common practices are not only inadequate and ineffective, but also that new and until now untested methods of treatment, such as increasing patients’ testosterone levels, are the way to go in the battle with prostate cancer.

Friday, November 21, 2014

What Luteinizing hormone values tells about natural testosterone production?

LH is an important hormone produced by the pituitary gland for both men and women. In women, it works as part of the menstrual cycle. In men it serves to maintain and produce testosterone and sperm. It is important to stay within a normal range of secretion in order to keep these body functions working correctly and to ensure the general health of your pituitary gland.

To check secretion levels you can request a blood test. Before you go, be aware that tests results may vary, and getting different results even minutes apart is quite normal. Many people become concerned with the differing levels of normal, as they want to be high normal in their levels of testosterone as opposed to low normal.

While high normal is more effective for your body, low normal is not necessarily bad, especially since levels fluctuate regularly. So do not be surprised if your LH levels vary while your levels of testosterone remain consistent.

The true value of measuring LH using a single measure test

It’s a known truth that LH levels can change from minute to minute. This makes small changes in daily production nearly undetectable through testing. An example from another article (source below) gives a comparison of the LH test represented by judging a better hitter in baseball on one hit.

Will the player who has hit better all season necessarily win? No, but that’s why batting averages are made up of every single at-bat. We must think of LH in the same way. The whole (being at a normal level) is more important than the individual highs and lows within normal.

A variable better suited for that kind of test would be something like “Who has blue eyes” or “Who is younger”. Variables like age and eye color do not change. The nature at which the LH changes makes a single measure much less useful in determining daily levels.,

Why the test is still important

While the test cannot give precise information on miniscule daily rises and falls in LH levels, what it can do is indicate when you are dangerously low.

The test will be able to tell you when your pituitary gland is about to go into hypopituitarism. Considering the range of things controlled by your pituitary gland, such as the thyroid, adrenal gland, ovaries, testes, and kidneys, it important to know if you are below average.

The symptoms of hypopituitarism include abdominal pain, fatigue, loss of body hair, shortened height (if during a growth spurt), vision issues, and weight loss, among others. The test is not made to worry about being high or low normal, but it can keep you safe from larger issues.

What can be done if you’re still wanting higher levels of LH?

The problem with recommending drugs to increase levels of a hormone that is hard to measure is that we really cannot gauge the effectiveness of the drug. Some have tried a DAA supplement regimen, but you’ll really only benefit from that if you are consistently low normal. Since we cannot tell how close to a blood peak each test is, worrying about these levels is unnecessary unless your levels are below average.

As long as your LH and testosterone both read some kind of normal, there is no need for worry. But if you’ve got it in your head that you need some kind of measure, the best you can do it measure how the DAA is affecting your testosterone.

Monday, November 3, 2014

Liver damage while on oral steroids

Steroids consumption is associated with a range of side effects, but when it comes to oral steroids liver damaging is the most common. For this main reason, most of steroid users advice to use injectables instead of orals which bedevil the good activity of liver.

In spite of this, oral steroids continue to be largely used by people worldwide. How this can be explained? First of all, injectable steroids can be detected in the blood long time after ending a steroid cycle. In case of orals, traces can be found few weeks after the last ingested pill. It may seem a long time too, but in compare with injectables this frame of time is quite shorter.

On the other hand, there are individuals who fear needles and will do all to avoid dealing with them. In this case, oral injectable is going to be used to replace the gains injectable can cause in human body. Oral steroids are more convenient to use, but are while less effective than injectable.

How is liver damaged while running oral steroid cycle?

Liver is one of the most important organ in human as that if it shuts down we have only 2-3 days to live.  It’s the “cleanser” of  the body, helping to get rid of toxins. Fortunately for us, liver has the capacity to regenerate and be functional even when 75% of it is damaged.

All 17A oral steroids are modified in a way to avoid degradation in the liver and be able to get in the blood. These kinds of steroids are toxic to liver because they inhibit the excretory function of the liver. Likewise, liver can get rid of toxic and they accumulate in the body. Known as cholestasis this is the most common disease caused by 7aa oral steroids are blamed for.

If no action is taken then after a while this disease worsens and may turn into cirrhosis, a stage where the activity begins to slow down. Worth to be mentioned cholestasis is not a lethal disease and is reversible if needed measures are taken on time. The best is to avoid getting to this stage at all, as ideal is to keep your liver safe instead of trying to treat.

The things get worse when two 17A oral steroids are taken concomitantly. Never admit this mistake. Always try to cycle an oral steroid along with an injectable one, this being the smart way of using steroids.

What are the most liver toxic oral steroids?

Don’t put all oral steroids in the same light as not all of them are liver toxic. Some of them are more toxic than others, while a minority has no bad influence on liver at all.

Top most liver toxic oral steroids are:

Superdrol

Dymethazine

Halodrol

Epistane

DHEA

Epiandrosterone

The more potent is the steroid, the higher is the toxicity level it carries on. Therefore, avoid using a powerful oral steroid when looking for fast and impressive muscle gains.

Top of less liver toxic oral steroids:

Winstrol,

Dianabol,

Anadrol.

So, only 17-aa steroids are liver toxic, while all other steroid have minor to no influence at all. A good idea is to stack a 17aa steroid with a non one in order to keep your liver functional while enjoying noticeable gains in muscle mass.

Symptoms of a damaged liver

When your liver function is perturbed because of oral steroid use there are series of signs that you have to worry about. Pay a close attention to your overall feeling when running a steroid cycle to be able to prevent any disease before it will to late.

Here are some of signs that should alarm you when taking orals:

-Lowered appetite;

-Fever associated with nausea (many take it as a cold , but it is not);

-Itchiness;

-Yellowish skin or eyes;

Whenever one of these signs occurs is time to take a break and revise what you are doing wrong. The earlier you acknowledge what happens in your body and give a hand of help, the higher chances to pass through a cycle with your liver function untouched.

The best would be not to wait for these signs, but simply take enzymes before and after steroid cycle. Few weeks later after the cycle is finished repeat the tests and see how it shows. This way you will have a closer look on your liver situation.

Products that help keep liver health while on steroids

As we said is better to prevent than to treat. A range of supplements available online are able to ensure a proper function of liver while taking 17aa steroids. LIV 52 and Milk Thistle, Essentiale  are just few of them, while a simple search on Google would list you a  longer list. Whatever you choose, make sure you have one of these supplements in your cycle.

If you already have liver problems than taking 17aa steroid is a bad idea. Thier use will worsen your condition so that it can turn into something irreversible. Go with injectable in this case or use non-17 aa anabolics.

Protect your liver before it is too late. Make sure your liver is 100% health before getting involves in a 17aa steroid cycle and make sure you add in some supplements able to help you liver cope with bad effects of steroids. Do you tests and keep an eye on signs which talks about a liver problem.

Monday, October 27, 2014

Deca Durabolin and recovery of testosterone production

Do you know Deca Durabolin is also known as Nandrolone Decanoate? Yes, it is an inject-able anabolic steroid. It is the most common and popular form of Nandrolone. Due to the attachment of the Decanoate to the Nandrolone the release times as well as the half life of the steroid can be spread out for more convenience in injections.

While at first, it saw many medical uses, the modern FDA cut back its uses to treating anemic patients, HIV/AIDS patients, and any others who were losing muscle mass due to their condition. It is still widely available in the US, despite cessations and bans of many other steroids.

The Benefits of Taking Deca Durabolin

Deca Durabolin is considered mild in comparison to other anabolic steroids on the issue of side effects. Watch this video to see Deca benefits over one of the most powerful steroids- Tren. Over years of studies, it does not seem to exhibit the same rate of the usual side effects everyone associates with steroids, such as hair loss, aggression, and increases in blood pressure and severe changes in lipids, kidney functions and liver values. This makes it a very popular choice for many steroid users. Despite its popularity for the lack of side effects, it has one major drawback.

Deca Durabolin and recovery of testosterone productionDeca Dick: The Side Effect that Really Matters

One of the well known side effects of steroid use is an effect on testosterone levels. Different types of steroids result in different levels of decrease in production of testosterone. Deca Durabolin is one of the most powerful steroids in use, and thus it creates a serious and noticeable decrease in testosterone levels.

“Deca Dick” has become commonly used slang to describe those on the steroid with Erectile Dysfunction. It is a hot topic in every forum and unfortunately for Deca Durabolin users, not only is it incredibly potent, but also has a higher recovery time for the user to recover to regular testosterone levels.

Is there more to low testosterone than just ED?

Most people know that lower testosterone levels will decrease a man’s libido. But there are a number of other risks and side effects of low testosterone levels that are often forgotten in the wake of erectile dysfunction. Some of these side effects include increased body fat, fragile bones, swelling and tenderness of breast tissue, hot flashes, and increased fatigue.

It can also affect sleep cycles and cause depression. These issues, which could develop into more serious problems, should be kept in mind along with ED when considering the benefits of Post Cycle Therapy.

The Benefits and Importance of Post Cycle Therapy (PCT)

Post Cycle Therapy can be crucial to increasing testosterone levels at a more desirable rate. PCT is much more than just recovering testosterone. PCT helps to keep your entire endocrine system healthy. In the early days of steroids in the 50’s, 60’s, and 70’s not much was known about their effects on the endocrine system. It wasn’t until the 80’s or 90’s that doctors and scientists realized the extent to which steroids affected the Hypothalamic Pituitary Testicular Axis (HPTA). PCT was born out of this revelation, and has been encouraged ever since.

The Results of Skipping PCT

While a body can usually rebalance itself in 1 to 4 months that could be counteractive to the benefits of the steroid cycle it as the imbalance has enough time to affect the body in multiple ways. Decreasing the time it takes the body to regain testosterone levels (which can be as low as 75% decrease in Deca Durabolin users) can ensure the health of the endocrine system as well as the avoidance of other symptoms that come with below average testosterone levels.

Conclusion

Deca can indeed cause you huge muscle growth, but wrong use can also lead to serious side effects. In order to stay safe and enjoy great results, educate yourself about Deca proper usage, side effects, stacks, recommendations and things to avoid.  PCT is just one of them and play a big role.

Wednesday, October 15, 2014

Growth hormone deficiency in children

Growth hormone deficiency means the pituitary gland does not make enough growth hormone.


The pituitary gland is located at the base of the brain. This gland controls the body’s balance of hormones. It also makes growth hormone. This hormone causes a child to grow.
Growth hormone deficiency may be present at birth (congenital). Or it may be the result of medical condition. Severe brain injury may also cause growth hormone deficiency.
Children with physical defects of the face and skull, such as cleft lip or cleft palate, may have decreased growth hormone levels.
Most of the time, the cause of growth hormone deficiency is unknown.

Symptoms
Slow growth may first be noticed in infancy and continue through childhood. The pediatrician will usually draw the child's growth curve on a growth chart. Children with growth hormone deficiency have a slow or flat rate of growth. The slow growth may not show up until a child is 2 or 3 years old.
The child will be much shorter than most children of the same age and gender. The child will still have normal body proportions though body build may be chubby. Often the child’s face looks younger than children of the same age. The child will usually have normal intelligence.
In older children, puberty may come late or may not come at all, depending on the cause.

Exams and Tests
A physical examination, including weight, height, and body proportions, will show signs of slowed growth rate. The child will not follow the normal growth curves.
Hand x-ray can determine bone age. Normally, the size and shape of bones change as a person grows. These changes can be seen on an x-ray and usually follow a pattern as a child grows older.
Testing is usually done after the  pediatrician has looked into other causes of poor growth. Tests that may be done include:
Growth hormone causes the body to make insulin-like growth factor (IGF1) and insulin-like growth factor binding protein 3 (IGFBP3). Tests can measure these growth factors.Accurate growth hormone deficiency testings involves a stimulation test. This test takes several hours.
MRI of the head can show the hypothalamus and pituitary glands.
Tests to measure other hormone levels may be done because lack of growth hormone may not be the only problem.

Treatment
Treatment involves growth hormone shots (injections) given at home. The shots are usually given once a day. Older children can often learn how to give themselves the shot.
Treatment with growth hormone is long-term, often several years. During this time, the child needs to be seen regularly by the doctor to ensure treatment is working and to change the dosage of the medicine if needed.
Serious side effects of growth hormone treatment are rare. Common side effects include:

    Headache
    Fluid retention
    Muscle and joint aches
    Slippage of the bones at the hip

The earlier the condition is treated, the better the chance that a child will grow to near-normal adult height. Many children gain 4 or more inches over the first year and 3 or more inches during the next 2 years. The rate of growth then slowly decreases.

Friday, October 3, 2014

The Benefits of Human Growth Hormone

Human Growth Hormone, commonly known as HGH is a protein based peptide hormone of incredible anabolic properties and functions found in all human beings and essential for a host of functions within the human body. While HGH therapy has existed for many years safe and effective administration was not available until the mid-1980’s when synthetic versions first hit the shelf; prior to this period the only way one could obtain Human Growth Hormone for therapy was from direct extraction from the pituitary of cadavers; an often dangerous and unsanitary practice. However, by the late 1990’s and early 2000’s HGH in a biosynthetic form was now highly available and since that time it has been one of the most sought after hormones in both hormone replacement therapy and the world of performance enhancement. Commonly referred to as the fountain of youth hormone HGH has been shown to produce enumerable traits in preserving youth and vigor as well as muscular development and improved metabolic efficiency. Even as Human Growth Hormone remains one of the more expensive hormones to purchase, as its benefits are great and its safety record is nearly perfect it remains highly popular despite the price one may pay.

The Benefits of Human Growth Hormone:
To understand the benefits of Human Growth Hormone we can largely see them by simply understanding its basic function(s) as discussed above; however, unfortunately as we age such benefits began to fall short as natural HGH production declines as we age and often at a rapid rate. For this reason more and more people the world over, both men and women have begun supplementing with biosynthetic Human Growth Hormone in an effort to avoid such a crash, as well as many athletes from baseball to football, track & field to bodybuilders and power lifters, gym rats and everything in-between. While therapeutic doses aimed at slowing down the signs of aging are common, as it pertains to the athletic world and performance enhancing doses are commonly much higher as the idea here is not to simply provide adequate levels but to surpass them so that the benefits can become further enhanced.

Through the use of supplemental Human Growth Hormone the individual can expect to reap the rewards of several beneficial applications and they apply universally to all who use it regardless of purpose; however, the rate of acceleration and the total end will largely vary from one to the next based on dosing and the coupling of anabolic androgenic steroids. Anabolic steroid use is very common with HGH use in the athletic world as both act in a means to work together enhancing the effects of each.

Those who administer biosynthetic HGH can largely expect a host of beneficial attributes such as muscle tissue growth, higher metabolic rates, a leaner and tighter physique, increased recovery within the body, increased bone, joint and tendon strength, healthier looking skin, as well as increased energy. While these are largely the physical attributes in their general sense, Human Growth Hormone goes far beyond the direct physical and holds other very important traits as well. Those who supplement with Human Growth Hormone will find they possess a greater clarity of thought and focus as well as enhanced moods overall as HGH can largely stave off such problems as depression. If levels of HGH in the body fall below optimal range each one of the positive benefits just discussed begins to decline as well; this is why as you can see proper levels are very important. In that same light, as levels increase beyond natural production each and every beneficial attribute is enhanced to degrees previously deemed unimaginable.

Real Human Growth Hormone:
As is common in the world of anabolic steroids, as HGH is not an anabolic steroid in any shape or form, like many steroids it is often counterfeited, so much so it is without question the most commonly counterfeited hormone in the performance enhancing world when purchased on the black market. Moreover, in recent years due to HGH popularity increasing many legal peptide fragments have hit the shelves; these fragments are often a partial Human Growth Hormone medication but this is like buying half a sandwich and one that won’t digest properly. While these fragment peptides are generally safe they are also generally worthless. When you are looking to obtain true blue Human Growth Hormone stay away from the generic black market brands and stick with true manufactures of the hormone such as Humatrope, Saizen, Serostim and Nutropin to name a few.

Human Growth Hormone Cycles and Doses:
Because it possesses such a high safety rating Human Growth Hormone can be used indefinitely; there is no max time frame in-which we must hold to. However, as beneficial as the hormone is it will take a long time to see such benefits; a few weeks of HGH therapy is a waste of money and a complete waste of good HGH. To reap a true benefit 16 weeks is generally the minimal amount of time you’ll want to supplement with HGH with 6 months being far more optimal. While this can be expensive consider this; the effects of Human Growth Hormone are largely permanent and that is worth noting.

Depending on your purpose the dose may vary from person to person. Human Growth Hormone is normally dosed in International Units or IU and as such, in therapeutic cases 1iu per day is very common place among both men and women with it occasionally going up to 2iu per day. However, for the performance enhancer, as it pertains to women 2iu per day will often prove to be perfect; while 2iu per day will provide many beneficial effects for men, notably fat-loss, to receive a full anabolic effect 4iu will prove to necessarily be optimal. While 4iu is highly beneficial and generally safe, the individual will not notice much difference in doses that are in the 5-6iu range; it is not until we get into the double digit doses that effects are greatly enhanced beyond the 4iu mark. However, although the side-effects of HGH are rare, when we delve into these very high doses they are almost guaranteed.

Monday, September 29, 2014

Low Testosterone

Low testosterone is a conditioned suffered by millions of men and while remedy is readily available the vast majority does little to nothing about it. In some cases it could be laziness but in most it’s simply a lack of education; when you don’t know or understand something the simplest thing in the world can be akin to trying to understand the most complicated aspects of human thought. Even so, while many men remain in the dark increasingly many more are coming into the light so to speak and doing something about their low testosterone problem; after all, it is a condition no man has to live with and once remedied the normal statement is “why didn’t I do this sooner?”

As education has begun to increase so have the myths and lies that surround it, as the only true treatment for low testosterone is anabolic steroids; this should come as no surprise. Many men are so afraid of anabolic steroids they’ll do anything to avoid them even if it means convincing themselves of half-truths; as the old saying goes, it’s not a lie if you believe it but unfortunately it simply doesn’t work this way. In truth, to understand low testosterone and the treatment involved you need to understand anabolic steroids and when you understand them you’ll understand they are not medications in the common sense of the word but rather synthetic hormones identical to the ones you already produce; however, as you now suffer from low testosterone you now produce far less.

Low testosterone can affect a man negatively in a host of ways from ruining his physique, draining his energy, destroying his sexual performance or even desire to a host of other mental and physical problems. Many men often attribute this to age but it doesn’t have to be this way and in-fact, man was not intended to fall into this state; much of it is often brought on by us. While this remains true and taking care of one’s self will aid in keeping testosterone levels adequate many times that is not enough. There are things you can do to aid in remedy in a natural sense but if you truly suffer from low testosterone actual testosterone therapy is going to be the only course of true action.

We have taken some of the most common myths revolving around low testosterone and the treatment thereof and left you with only the truth. While you find there is still much more to learn hopefully you’ll find this to be a good starting point. Each and every myth discussed is taken right from some of the most popular message boards that deal in such discussion but it is here we will put some of these myths to rest.

Myth:

If you suffer from true low testosterone brought on simply by age you can remedy the problem with diet and exercise.

Truth:

It is true, exercise can increase testosterone levels and some foods have been shown to do the same; foods such as eggs and red meat are two very good foods for aiding in such a cause but the increase in testosterone from diet and exercise is so miniscule that for an individual suffering from low testosterone it’s hardly worth mentioning. If you suffer from low testosterone and desire a remedy the only remedy that will aid in your cause is true testosterone therapy.

Myth:

Once you begin testosterone therapy and your levels return to normal you will eventually be able to discontinue therapy and remain at a stable level.

Truth:

If you suffer from true low testosterone you will always suffer from low testosterone; if you are over the age of 40 this is guaranteed and in many cases those over 30 years of age will find the same to be true. However, while continuous lifelong therapy sounds very annoying isn’t it better than low testosterone; of course it is. Now there is an exception to this rule; an individual who has brought low testosterone upon himself due to years of anabolic steroid use may be able to stimulate natural testosterone production again to an adequate level and discontinue therapy once this is achieved; however, while possible it is unlikely. Any individual over the age of 40 will never be able to accomplish this and even a younger individual will have a very difficult time.

Myth:

Low testosterone treatment plans are all the same as the hormone in each is simply that of testosterone.

Truth:

Testosterone therapy can occur in many forms, from injectable and transdermal creams and patches and even subcutaneous pellets implanted under the skin. In the end it is true, with each form of therapy you are receiving the same testosterone hormone but the efficiency and effectiveness of each form varies greatly. Without question injectable testosterone is the most efficient and effective form of testosterone therapy, as through injections the needed testosterone is placed directly into the blood. While transdermal medications will absorb into the blood many men find difficulty in achieving proper levels with this form making it the least desirable of the four. If injections are not an option for whatever reason testosterone implant pellets are a fine choice and often all the testosterone an individual will need.

Tuesday, September 23, 2014

Dangers of Steroid Abuse

All anabolic steroid use not prescribed by a licensed physician, is more properly defined as “steroid abuse”.  The reason for this is simple, “Steroids are very powerful hormones that can be extremely dangerous!”  They can cause a variety of health problems some of which can have lasting ramifications.  Although the twenty-three steroid related dangers listed below are not exhaustive, they certainly illustrate the risks and potentially harmful effects abusers face.

    Stunted growth.  Steroids can cause advancement and fusion of the epiphysis (growth plates in the bones).  As androgen levels rise it leads to bone age advancement.  When the bone plates are completely fused, growth is finished.  Furthermore, over-treatment with steroids can result in growth deceleration (slowing of the rate of growth).
     Increased risk of HIV and Hepatitis.  Because anabolic steroid users often do not have access to appropriate amounts of clean and sterile needles, or do not follow appropriate injection protocol, there is an increased risk of contracting HIV or other bloodborne pathogens.
    Increased risk of hair loss.  Anabolic steroids can convert to variants of Dihydrotestosterone, the recognized cause of premature hair loss.  In addition to contributing to loss, steroids can also expedite the process of male pattern baldness in predisposed users.
    Hypogonadism, the shrinking of testicles.  Because the body’s natural testosterone is no longer needed when anabolic steroids are administered, the body halts production of its own supply of testosterone results in a shrinking of the testicles.
    Increased risk of bodily hair growth.  This happens throughout the body, but not on the head, of both men and women.
    Elevated blood pressure.  Due to their ability to raise red blood cell count and Hematocrit levels, steroids can cause blood pressure to rise significantly.
    Increased amounts of LDL cholesterol (the bad kind).  This excess tends to remain on the cell walls causing conditions like atherosclerosis and heart disease.  An elevated LDL can generate a negative shift in triglycerides, which contribute to serious health problems.
    Lowered HDL cholesterol (the good kind).  HDL cholesterol is very dense, and actually helps to clear debris from arterial walls.  Lowering HDL cholesterol can increase the risk of coronary disease.
    Increased aggression.  Commonly referred to as “Roid Rage”, there is evidence that anabolic steroids contribute to increased aggressive behavior in some users.
    Addiction.  Although physical addiction to steroids is unlikely, the potential for psychological addiction is quite high.
    Enlargement of the left ventricle of the heart.  It has been well documented that coronary issues may result from the abuse of anabolic steroids, commonly beginning with the enlargement of the left ventricle.
    Liver toxicity. Orally administered anabolic steroids have been shown to increase the markers of liver function, and to cause liver toxicity.
    Edema (water retention). Elevated and imbalanced estrogen levels, coupled with increased sodium retention causes the user to retain water.
    Stroke.  Steroid use has been medically linked to an increased incidence of strokes.
    Steroids can lead to deathHeart attack.  Abusers of anabolic steroids face a variety of potential heart related complications, among which are an increased risk of heart attacks and the possibility of coronary disease.
    Prostate Enlargement.  Some steroids convert to Dihydrotestosterone and its variants, which can enlarge the prostate gland increasing the risk of urination problems and prostate cancer.
    Gynecomastia.  Certain steroids aromatize (convert to estrogen).  High levels of estrogen can cause the enlargement of mammary tissue in males, resulting in female-like breasts.
    Sexual dysfunction.  Some steroids directly cause a temporary of a loss of libido and sexual impotence.
    Infertility.  Some steroids cause a reduction in sperm count, resulting in decreased ability to reproduce.
    Deepening of the voice.  Although it occurs naturally in both men and women, steroid use can further deepen one’s voice.
    Clitoral hypertrophy.  Women who abuse steroids may experience an irreversible increase in clitoris size.
    Menstrual problems.  Female abusers may experience cycle irregularities, a hindrance or loss of menstruation, and further problems all of which contribute to a decline in reproductive ability.  

Tuesday, August 26, 2014

Low Testosterone Myth and Truth

Low testosterone is a conditioned suffered by millions of men and while remedy is readily available the vast majority does little to nothing about it. In some cases it could be laziness but in most it’s simply a lack of education; when you don’t know or understand something the simplest thing in the world can be akin to trying to understand the most complicated aspects of human thought. Even so, while many men remain in the dark increasingly many more are coming into the light so to speak and doing something about their low testosterone problem; after all, it is a condition no man has to live with and once remedied the normal statement is “why didn’t I do this sooner?”

As education has begun to increase so have the myths and lies that surround it, as the only true treatment for low testosterone is anabolic steroids; this should come as no surprise. Many men are so afraid of anabolic steroids they’ll do anything to avoid them even if it means convincing themselves of half-truths; as the old saying goes, it’s not a lie if you believe it but unfortunately it simply doesn’t work this way. In truth, to understand low testosterone and the treatment involved you need to understand anabolic steroids and when you understand them you’ll understand they are not medications in the common sense of the word but rather synthetic hormones identical to the ones you already produce; however, as you now suffer from low testosterone you now produce far less.

Low testosterone can affect a man negatively in a host of ways from ruining his physique, draining his energy, destroying his sexual performance or even desire to a host of other mental and physical problems. Many men often attribute this to age but it doesn’t have to be this way and in-fact, man was not intended to fall into this state; much of it is often brought on by us. While this remains true and taking care of one’s self will aid in keeping testosterone levels adequate many times that is not enough. There are things you can do to aid in remedy in a natural sense but if you truly suffer from low testosterone actual testosterone therapy is going to be the only course of true action.

We have taken some of the most common myths revolving around low testosterone and the treatment thereof and left you with only the truth. While you find there is still much more to learn hopefully you’ll find this to be a good starting point. Each and every myth discussed is taken right from some of the most popular message boards that deal in such discussion but it is here we will put some of these myths to rest.

Myth:
If you suffer from true low testosterone brought on simply by age you can remedy the problem with diet and exercise.

Truth:
It is true, exercise can increase testosterone levels and some foods have been shown to do the same; foods such as eggs and red meat are two very good foods for aiding in such a cause but the increase in testosterone from diet and exercise is so miniscule that for an individual suffering from low testosterone it’s hardly worth mentioning. If you suffer from low testosterone and desire a remedy the only remedy that will aid in your cause is true testosterone therapy.

Myth:
Once you begin testosterone therapy and your levels return to normal you will eventually be able to discontinue therapy and remain at a stable level.

Truth:
If you suffer from true low testosterone you will always suffer from low testosterone; if you are over the age of 40 this is guaranteed and in many cases those over 30 years of age will find the same to be true. However, while continuous lifelong therapy sounds very annoying isn’t it better than low testosterone; of course it is. Now there is an exception to this rule; an individual who has brought low testosterone upon himself due to years of anabolic steroid use may be able to stimulate natural testosterone production again to an adequate level and discontinue therapy once this is achieved; however, while possible it is unlikely. Any individual over the age of 40 will never be able to accomplish this and even a younger individual will have a very difficult time.

Myth:
Low testosterone treatment plans are all the same as the hormone in each is simply that of testosterone.

Truth:
Testosterone therapy can occur in many forms, from injectable and transdermal creams and patches and even subcutaneous pellets implanted under the skin. In the end it is true, with each form of therapy you are receiving the same testosterone hormone but the efficiency and effectiveness of each form varies greatly. Without question injectable testosterone is the most efficient and effective form of testosterone therapy, as through injections the needed testosterone is placed directly into the blood. While transdermal medications will absorb into the blood many men find difficulty in achieving proper levels with this form making it the least desirable of the four. If injections are not an option for whatever reason testosterone implant pellets are a fine choice and often all the testosterone an individual will need.

Monday, August 18, 2014

Oral Turinabol (Chlordehydromethyltestosterone)

Oral Turinabol is one of those substances that has gained what I would call a 'quiet cult status' amongst bodybuilders. It was first developed by scientists in East Germany for use by their Olympic athletes. The success achieved by those athletes is testament to its effectiveness. The fact that it was used extensively for enhancing sports performance also meant that it was subject to many trials with documented results proving very impressive.

So what does Oral Turinabol have to offer that is so special?

Well it does provide good lean muscle gains and, although strength and muscle increases will not be as dramatic as with some other compounds, they will be less likely to be accompanied by water retention. This means that you are more likely to keep any gains made when coming off a cycle. In addition to this, Oral Turinabol does not create estrogen related side effects (e.g. gynecomastia) although it is 17-alpha alkylated which means it can be toxic to the liver so it is wise to use some form of liver support when on a cycle (e.g. Silymarin, Dandelion, NAC).

Oral Turinabol has been described as a derivative of Dianabol although it does have a much lower level of androgenic activity. Studies have revealed it to have anywhere from 0 - 6 in terms of androgenic effects and 53 for anabolic effects (based on a score of 100 each for testosterone). This means that it will not give you the bloated, puffy look often observed by those who use Dianabol. In fact, many users have compared it to Anavar in terms of results.

SIDE EFFECTS

Negative side effects are rare with this substance and are usually the result of using cycles that are either too long or too high in dosage. The aforementioned risk of liver toxicity and a lowering of the clotting ability of the blood are the only things to really look out for. It has also been implicated as regards the lowering of natural testosterone levels, but once again this is generally dose related. There have been reports of women suffering more adverse side effects than men when using this substance, however these reactions occurred in women who were taking almost double the amount taken by their male counterparts, so of course they would get more side effects!

DOSAGE

It has been recommended that men should take between 20-40mg every day and women 5-10mg/day. However, in real life terms male bodybuilders usually prefer an amount of 0.4mg per pound of bodyweight.
One of the many interesting things about Oral Turinabol is its ability to reduce SHBG's binding to other steroids, which leads to the freeing up of more testosterone in the body. For this reason many athletes find it a valuable accompaniment to any cycle - particularly those involving the use of testosterone. The fact that Oral Turinabol is not associated with aromatization (i.e. conversion to estrogen) also adds to its attractiveness.

All in all, when you consider the fact that it produces little in the way of troublesome side effects (when used in reasonable dosages) and produces a high quality gain in muscle mass over time, Oral Turinabol is definitely worth considering as part of an effective cycle. Even used on its own it will definitely produce a noticeable improvement in mass and strength. The gains will not be astounding but they will be more easily maintained since the improvements made on Oral Turinabol are not an illusion created by water weight.

Tuesday, August 12, 2014

IGF-Long R3 - A Powerful Upgrade on IGF-1 that causes an Explosion of Muscles

Anybody who's into bodybuilding or research has probably heard of IGF-1, which stands for insulin-like growth factor. IGF-1 is a growth-promoting polypeptide that plays a key role in promoting muscle growth, development and healing.

Furthermore, it's also a major hormonal mediator that supports statural growth in children. I don't think too many children have subscribed to this newsletter, though, so we'll keep the bone-growth discussion to a minimum.

Under normal instances, growth hormone (GH) attaches itself to its receptors located in the liver and other tissues and rouses the synthesis of IGF-1. In target tissues, the Type 1 IGF receptor, which is homologous to the insulin receptor, gets triggered by IGF-1.

This action leads to intracellular signaling that goes ahead and promotes stimulation of a variety of process that all lead to muscular and/or statural growth (in children). IGF-1 metabolic actions are concentrated at motivating glucose, amino acids and fatty acids uptake; this cause of action helps the metabolism support tissue growth. Summing everything up here, IGF-1 is made in response to GH and helps the latter have a very positive effect on muscle and/or bone growth (in children).

Now we come to the peptide known as IGF-1 Long R3, which some researchers might not be so familiar with….

How do IGF-1 Long R3 and regular IGF-1 differ?

Normal IGF-1 consists of 70 amino acid chains and is structurally similar to insulin, hence the "insulin-like" part of the name. IGF-1 is an exceptional anabolic peptide that performs insulin-like actions such as transporting certain amino acids and glucose into the correct muscle cells, where they are proposed and turned into new muscle tissue.

IGF-1 Long R3 is a chemically altered version of IGF-1 that's designed to be more powerful. This peptide features 83 amino acid chains, with Arg(R) in place of Glu(E) at position three, which is where the "R3" comes from. The R3 allows this peptide to avoid binding to proteins, thus giving IGF-1 Long R3 a longer half life – usually over 20 hours, as opposed to IGF-1's half life of 20 minutes.

What you get with IGF LR3 is a long-acting, extremely potent peptide that works to increase muscle mass and make muscle tissue more sensitive to insulin, often producing a decrease in fat storage.

IGF-1 Long R3 Benefits:

    It gathers fat that is then used as energy in adipose tissue.
    Has the power to restore impaired tendons.
    Promotes and stimulates protein synthesis.
    Causes hyperplasia, which is in essence the upsurge of more muscle cells.
    Responsible for muscle mass building and stimulates/enhances fat loss.
    IGF-1 Long R3 transports nutrients straight into cells and muscles, thus further promoting maximum results.

IGF-1 Long R3 forms a great stabilizer that promotes cellular culture. The IGF-1 LR3 peptide easy adapts to numerous cell varieties and has quality effects that are essential for growth. The LR3 forms up a lasting analog of human IGF-1 that was created for mammalian cell culture that facilitates large-scale development of recombinant biopharmaceuticals.

The recombinant Human LR3 insulin, such as the Growth factor-1 which is generated from the E.Coli, serves as a solo non-glycosylated polypeptide chain that carries 83 amino acids and contains a molecular mass of 9.1 Da.

Long R3 IGF-1 is capable of performing a variety of functions such as:igf1

    Increasing RNA
    Increasing Protein Synthesis
    Promoting Fat Metabolism
    Promoting Sugar Transport
    Promoting efficacy of Nutrient Intake

Long R3 IGF-1 plays a positive role in the promotion of muscle tissue, plus it supports and multiplies nitrogen retention and augmented food conversion. It generally helps the body make use of nutrients in a more efficient manner.

The remarkable abilities of Long R3 IGF-1 are boosted by the addition of Growth Hormone (GH). As the body undergoes puberty, IGF oversees natural muscle growth that occurs during these years. There are a variety of things that get done by IGF in the human body.


Benefits of IGF-1 in General:

The most positive effects include the following: increased amino acid shuttling to cells, doubled glucose transportation, tripled protein synthesis, decreased protein deprivation and increased RNA synthesis.

When IGF-1 becomes active, it acts differently in separate tissue masses. When it comes to muscle cells, proteins and associated cell components become stimulated. Protein synthesis gets amplified alongside amino acid immersion.

When it comes to energy production, IGF-1 consolidates fats for use as energy in adipose tissue. When it comes to lean tissue, IGF-1 stops insulin from shuttling glucose across cell membranes. This move ensures that the cells are left with the option of burning off fat as a source of energy.

IGF-1 also takes up the role of insulin in the body. It helps muscles become rather sensitive to insulin's effects. This role has helped many insulin users minimize their insulin dosage by a specific margin; however, they attain the equivalent effects.

The most outstanding and interesting potent effect that IGF-1 has on the human body is its capability to cause cells to split (Hyperplasia). This process results in major muscle growth.