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Showing posts with label steroid. Show all posts
Showing posts with label steroid. Show all posts

Friday, December 19, 2014

How to protect liver during steroid cycle

Steroids are blamed for many negative effects on human body, one of them being liver toxicity. But not all of them are responsible for damaging the liver. All alkylated anabolic steroids are proved to have bad influence in liver function. What are these steroids? All oral anabolics with the most common of them in the top: Dianabol, Anadrol, Anavar and of course Winstrol.

Non-alkylated steroids are injectable steroids like Testosterone, Masteron, Equipoise, Deca Durabolin, Primobolan and others. If you want free of liver effects steroids than choose one of this group. This is especially important for those who are susceptible to liver problems.

Liver has the role to clean our body of toxins. Steroids are toxins, hence when they enter the body begin to eliminate them, without letting them get in ten blood. To avoid being breakdown into liver, oral steroids were modified in a way that inhibits the excretory function of the liver. It is not able to eliminate toxins; hence they accumulate in the body causing serious health problems.

We wrote about how oral steroids destroy liver, so will will not detail too much this subject. To read more about it click  on this article “Oral Anabolic Steroids, Liver Enzyme Tests and Liver Function“.

The intend of this post is to show how to break through a steroids cycle keeping your liver fully functional. Read further and find how exactly you can do it.

Use a non-alkylated steroid as base

The use of oral steroids alone is contraindicated. It put a high pressure in the liver and it may cede. Even you have a healthy liver, always stack an injectable with an oral. Such a mix has also a great synergic effect. So that you do not only manage to protect your liver, but also accomplish great results, whether you are bulking or cutting.

The dosage has to be no higher than 350-750mg per week of stack. A higher dosage will inhibit liver function even the gains will be better then you expected. You may get bigger or slimmer, but your liver is goanna be deeply affected. Just to know, individuals can live only 2-3 days if liver function is shut down.

Read this ” Building muscle using therapeutic dosages of steroids to find out how” to understand that staying on minimal dosage still can provide you with nice gains.

Cycle duration has not to exceed 6 weeks. Of course there are many steroid users taking oral anabolics for much longer time without apparently damaging the liver. Acting so is a a big mistake. What they miss is that with every week steroids cause scar tissue which is undetected. They worsen in time as steroids consumption don’t let them heal. The finality is that you get not only with big muscle, but also big scars which put you at risk to develop cancer.

Six weeks are the frame time within the activity of liver is still normal and steroids influence is not devastating. With proper manipulation great results can be achieved even within “short steroid cycle”.  High steroid dosage for long time are too dangerous for your health to risk it.

Choose short steroid cycle over long cyles. Read here why -  The pros of using short steroid cycles

If still want to make your cycle longer, than replacing orals with injectables is a must. For every gram of Winstrol or Anadrol take Testosterone, while Anavar can be replaced with Trenbolone in a 2:3 basis. Search for the injectable which carry the same effects the oral did and make the substitution beginning with the 7th week of cycling.

No bridging between cycles

Alkylated steroids cycles have to be followed by the same amount of time if not more. Allow body time to get back to its normal function. Liver regenerate if time is allowed. And so do hormones and other vital organs.

Don’t know exactly how long the break between cycles should be ? Find here -Time between steroids

It’s common nowadays to not stop taking steroids using bridging. Aside of damaging your liver, such a method is not productive. The more steroids take, the higher resistance body builds to it so that they become inefficient after a period of time. That’s why take breaks and let the body detach from toxins that entered it during time. After a while, you can get back in cycling.

Take supplements to protect liver

Despite of caution steroid use, including liver supplements in your diet is necessary. Lecithin, Liv-52 and Milk Thistle, Essentiale are some products to take in consideration but you are not limited to them. Buy from reliable sources to make sure you ingest high quality products. And this is available for anabolics too.

No alcohol or liver toxic medications

When cycling avoid drinking alcohol at all and be caution to drugs that shows liver toxicity properties. The liver activity is already perturbed, don’t worsen the situation.

Bottom line. Before get involved in oral steroid cycle make sure your liver function is normal. The same do when cycle is over and you are ready for the next one. Throw away the idea of oral cycle if you already have liver issues. It’s not for you. In all other cases keep in mind the above mentioned tricks and liver activity will not be affected in a degree that put your health in danger.

Thursday, June 26, 2014

Higher Steroid Hormone Levels in Pregnancy Can Cause Autism in Children

Researchers exploring the causes of autism have linked higher levels of steroid hormones in the womb during early fetal development to autism spectrum disorder.

These hormones, which play a key phase in brain development at three to four months of pregnancy, may also explain why the condition is far more common among males than females, they said.

But it was too early to say whether higher hormone levels were a cause of autism, the team wrote, and cautioned against hormone screening or treatment based on their preliminary findings.

Scientists at the University of Cambridge in Britain and Denmark's Statens Serum Institute analyzed hormone levels among nearly 20,000 stored samples of amniotic fluid, which surrounds the fetus in the uterus.

The team measured levels of four "sex" steroid hormones -- testosterone, progesterone, 17-alpha-hydroxy-progesterone and androstenedione -- which are known to play a role in brain development.

They also looked at a fifth hormone, cortisol, which is a marker of stress.

The researchers found higher hormone levels in the amniotic fluid in 128 males who were later diagnosed with autism spectrum disorder.

All autistic subgroups were found to have the signature: Asperger syndrome, classic autism or a category called unspecified pervasive developmental disorder.

"This is one of the earliest non-genetic biomarkers that has been identified in children who go on to develop autism," said Simon Baron-Cohen, a University of Cambridge professor.

"We previously knew that elevated prenatal testosterone is associated with slower social and language development, better attention to detail and more autistic traits.

"Now, for the first time, we have also shown that these steroid hormones are elevated in children clinically diagnosed with autism. Because some of these hormones are produced in much higher quantities in males than in females, this may help us explain why autism is more common in males."

It was not known what causes the higher steroid levels in the first place, and the team cautioned against using the findings as a tool to screen for autism.

Nor should drugs be used to block steroid hormones.

"This could have unwanted side effects and may have little to no effect," said Baron-Cohen.

Only males were tested in the first phase of research. The next step will be to see if a similar telltale exists for females.

"Steroid hormones are particularly important because they exert influence on the process of how instructions in the genetic code are translated into building proteins," co-researcher Craig Brierley said in an email exchange with AFP.

The study appeared in the journal Molecular Psychiatry.

The cause of autism, a complex neurodevelopmental disorder characterized by social withdrawal, is considered to be roughly split between genetic and environmental factors, according to a study last month in the Journal of the American Medical Association (JAMA).